Maduración pulmonar fetal: Efectos sobre la morbilidad respiratoria en prematuros tardíos
DOI:
https://doi.org/10.22529/me.2019.4(1)04Palabras clave:
SDR, neonatología, prematurez, oxigenoterapia, corticoidesResumen
Los recién nacidos entre las 34 y las 36 semanas de gestación (SEG), definidos actualmente como “prematuros tardíos” (RNPTT) requieren en mayor frecuencia de internación en unidades de cuidados intensivos neonatales, siendo la morbilidad respiratoria una de las principales causas de internación1 . El uso de corticoides prenatales ha demostrado mejorar la función pulmonar en prematuros extremos (<27,6 SEG), muy prematuros (28-31,6 SEG) y prematuros moderados, (32-36,6 SEG) pero no han sido evaluados en forma extensa en el período prematuro tardío y no existen datos concluyentes al respecto.Descargas
Referencias
Engle WA. A recommendation for the definition of «late preterm» (near-term) and the birth weight-gestational age classification system. Semin Perinatol. 2006;30(1):2-7. https://doi.org/10.1053/j.semperi.2006.01.007
Gyamfi-Bannerman C. Late Preterm Birth: Management Dilemmas. Obstetrics and Gynecology Clinics of North America. 2012;39(1):35-45. https://doi.org/10.1016/j.ogc.2011.12.005
Raju TNK, Higgins RD, Stark AR, Leveno KJ. Optimizing care and outcome for latepreterm (near-term) infants: a summary of the workshop sponsored by the National Institute of Child Health and Human Development. Pediatrics. 2006;118(3):1207-14. https://doi.org/10.1542/peds.2006-0018
Natarajan G, Shankaran S. Short- and LongTerm Outcomes of Moderate and Late Preterm Infants. Am J Perinatol. 2016;33(3):305-17. https://doi.org/10.1055/s-0035-1571150
Mahoney AD, Jain L. Respiratory Disorders in Moderately Preterm, Late Preterm, and Early Term Infants. Clinics in Perinatology. 2013;40(4):665-78. https://doi.org/10.1016/j.clp.2013.07.004
Clark RH. The epidemiology of respiratory failure in neonates born at an estimated gestational age of 34 weeks or more. J Perinatol. 2005;25(4):251-7. https://doi.org/10.1038/sj.jp.7211242
ACOG Committee ON Obstetric Practice. ACOG Committee opinion, no 475.Antenatalcorticosteroid therapy for fetal maturation. Obstet Gynecol. 2011; 117:422-4. https://doi.org/10.1097/AOG.0b013e31820eee00
Liggins GC, Howie RN. A controlled trial of antepartum glucocorticoid treatment for prevention of the respiratory distress syndrome in premature infants. Pediatrics. 1972;50(4):515-25. https://doi.org/10.1542/peds.50.4.515
Porto AMF, Coutinho IC, Correia JB, Amorim MMR. Effectiveness of antenatal corticosteroids in reducing respiratory disorders in late preterm infants: randomised clinical trial. BMJ. 2011;342 :1696. https://doi.org/10.1136/bmj.d1696
Gazquez Serrano IM, Arroyos Plana A, Diaz Morales O, Herraiz Perea C, Holgueras Bragado A. [Antenatal corticosteroid therapy and late preterm infant morbidity and mortality]. An Pediatr (Barc). 2014;81(6):374-82. https://doi.org/10.1016/j.anpede.2014.01.003
Ventolini G, Neiger R, Mathews L, Adragna N, Belcastro M. Incidence of respiratory disorders in neonates born between 34 and 36 weeks of gestation following exposure to antenatal corticosteroids between 24 and 34 weeks of gestation. Am J Perinatol. 2008;25(2):79-83. https://doi.org/10.1055/s-2007-1022470
Gyamfi-Bannerman C, Thom EA, Blackwell SC, Tita ATN, Reddy UM, Saade GR, et al. Antenatal Betamethasone for Women at Risk for Late Preterm Delivery. N Engl J Med. 2016; 80:230:8. https://doi.org/10.1097/01.ogx.0000489576.69844.54
Whitelaw A, Thoresen M.Antenatal steroids and the developing brain.Arch Dis Child Fetal Neonatal Ed. 2000; 83:154-7. https://doi.org/10.1136/fn.83.2.F154
Judith U. Hibbard. Consortium on Safe Labor, Respiratory morbidity in late preterm births. JAMA. 2010 28;304(4):419-25. https://doi.org/10.1001/jama.2010.1015
